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Publications

  1. Ioppolo, J. A., Caldwell, D., Beiraghi, O., Llano, L., Blacker, M., Valliant, J. F. & Berti, P. J. (2017) Nucl. Med. Biol. 52:32-41
    67Ga-labelled deferoxamine derivatives for imaging bacterial infection: Preparation and screening of functionalized siderophore complexes (link)

  2. Balachandran, N., To, F., & Berti, P. J. (2017) Biochemistry 56:592-601
    Linear Free Energy Relationship Analysis of Transition State Mimicry by 3-Deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) Oxime, a DAHP Synthase Inhibitor and Phosphate Mimic (link)
  3. Balachandran, N., Heimhalt, M., To, F., Liuni, P., Wilson, D. J., Junop, M. S. & Berti, P. J. (2016) Biochemistry 55:6617-6629
    Potent Inhibition of 3-Deoxy-D-arabinoheptulosonate-7-phosphate (DAHP) Synthase by DAHP Oxime, a Phosphate Group Mimic (link)
  4. Vito, A., Alarabi, H., Czorny, S., Beiraghi, O., Kent, J., Janzen, N., Genady, A. R., Ali-Karmi, S. A., Rathmann, S., Naperstkow, Z., Blacker, M., Llano, L., Berti, P. J. & Valliant, J. F. (2016) PLoS One 11:e0167425
    A 99mTc-Labelled Tetrazine for Bioorthogonal Chemistry. Synthesis and Biodistribution Studies with Small Molecule trans-Cyclooctene Derivatives (link)
  5. Lou, M., Gilpin, M. E., Burger, S. K., Malik, A. M., Gawuga, V., Popovic, V., Capretta, A. & Berti, P. J. (2012) J. Am. Chem. Soc. 134:12947-12957
    Transition State Analysis of Acid-Catalyzed Hydrolysis of an Enol Ether, Enolpyruvylshikimate 3-Phosphate (EPSP) (link)
  6. Lou, M., Burger, S. K., Gilpin, M. E., Gawuga, V., Capretta, A. & Berti, P. J. (2012) J. Am. Chem. Soc. 134: 12958-12969
    Transition State Analysis of Enolpyruvylshikimate 3-Phosphate Synthase (AroA)-Catalyzed EPSP Hydrolysis (link)
  7. Rob, T., Liuni, P., Gill, P. K., Zhu, S., Balachandran, N., Berti, P. J. & Wilson, D. J. (2012) Anal. Chem. 84: 3771-3779
    Measuring dynamics in weakly structured regions of proteins using microfluidics-enabled subsecond H/D exchange mass spectrometry (link)
  8. Jiang, S., Gilpin, M. E., Attia, M., Ting, Y.-L. & Berti, P. J. (2011) Biochemistry 50: 2205-2212
    Lyme Disease Enolpyruvyl-UDP-GlcNAc Synthase: Fosfomycin-Resistant MurA from Borrelia burgdorferi, a Fosfomycin-Sensitive Mutant, and the Catalytic Role of the Active Site Asp (link)
  9. Jackson, S. G., Zhang, F., Chindemi, P., Junop, M. S. & Berti, P. J. (2009) Biochemistry 48:11715-11723
    Evidence for Kinetic Control of Ligand Binding and Staged Product Release in MurA (Enolpyruvyl UDP-GlcNAc Synthase)-Catalyzed Reactions (link)
  10. Berti, P. J. & Chindemi, P. (2009) Biochemistry 48:3699-3707
    Catalytic Residues and an Electrostatic Sandwich That Promote Enolpyruvyl Shikimate 3-Phosphate Synthase (AroA) Catalysis (link)
  11. McCann, J. A. B. & Berti, P. J. (2008) J. Am. Chem. Soc. 130:5789-5797
    Transition State Analysis of the DNA Repair Enzyme MutY (link)
  12. McCann, J. A. B. & Berti, P. J. (2007) J. Am. Chem. Soc. 129:7055-7064
    Transition State Analysis of Acid-catalyzed dAMP Hydrolysis (link)
  13. Clark, M. E. & Berti, P. J. (2007) Biochemistry 46:1933-1940
    Enolpyruvyl Activation by Enolpyruvyl Shikimate 3-Phosphate Synthase (link)
  14. Zhang, F. & Berti, P. J. (2006) Biochemistry 45:6027-6037
    Phosphate Analogues as Probes of the Catalytic Mechanisms of MurA and AroA, Two Carboxyvinyl Transferases (link)
  15. Loncke, P. G. & Berti, P. J. (2006) J. Am. Chem. Soc. 128:6132-6140
    Implications of Protonation and Substituent Effects for C-O and O-P Bond Cleavage in Phosphate Monoesters (link)
  16. Berti, P. J. & McCann, J. A. B. (2006) Chem. Rev. 106:506-555
    Toward a Detailed Understanding of Base Excision Repair Enzymes: Transition State and Mechanistic Analyses of N-Glycoside Hydrolysis and N-Glycoside Transfer (link)
  17. Mizyed, S., Oddone, A., Byczynski, B., Hughes, D. W., & Berti, P. J. (2005) Biochemistry 44:4011-4017
    UDP-N-acetylmuramic acid (UDP-MurNAc) is a Potent Inhibitor of MurA (Enolpyruvyl-UDP-GlcNAc Synthase) (link)
  18. Lee, J. K., Bain, A. D. & Berti, P. J. (2004) J. Am. Chem. Soc. 126:3769-3776
    Probing the Transition States of Four Glucoside Hydrolyses with 13C Kinetic Isotope Effects Measured at Natural Abundance by NMR Spectroscopy. (link)
  19. Byczynski, B., Mizyed, S. & Berti, P. J. (2003) J. Am. Chem. Soc. 125:12541-12550
    Non-enzymatic Breakdown of the Tetrahedral (α-Carboxyketal Phosphate) Intermediates of MurA and AroA, Two Carboxyvinyl Transferases. Protonation of Different Functional Groups Control the Rate and Fate of Breakdown. (link)
  20. McCann, J. A. B. & Berti, P. J. (2003) J. Biol. Chem. 278:29587-29592
    Adenine Release is Fast in MutY-Catalyzed Hydrolysis of G:A and 8-oxo-G:A DNA Mismatches (link)
  21. Mizyed, S., Wright, J. E. I., Byczynski, B. & Berti, P. J. (2003) Biochemistry 42:6986-6995
    Identification of the Catalytic Residues of AroA (Enolpyruvylshikimate 3-Phosphate Synthase) Using Partitioning Analysis (link)
  22. Berti, P. J., & Tanaka, K. S. E. (2002) Adv. Phys. Org. Chem. 37:239-314
    Transition State Analysis Using Multiple Kinetic Isotope Effects: Mechanisms of Enzymatic and Non-enzymatic Glycoside Hydrolysis and Transfer (link)
  23. Chen, X.-Y., Berti, P. J. & Schramm, V. L. (2000) J. Am. Chem. Soc. 122:6527-6534
    Transition State Analysis for Depurination of DNA by Ricin A-Chain
  24. Chen, X.-Y., Berti, P. J. & Schramm, V. L. (2000) J. Am. Chem. Soc. 122:1609-1617
    Ricin A-Chain: Kinetic Isotope Effects and Transition State Structure with Stem-Loop RNA
  25. Berti, P. J. (1999) Methods Enzymol. 308:355-397
    Determining Transition States from Kinetic Isotope Effects
  26. Berti, P. J. & Schramm, V. L. (1999) Enzymatic Transition State Structures Constrained by Experimental Kinetic Isotope Effects in ACS Symposium Series No. 721/Transition State Modeling for Catalysis ; Trulhar, D. G., Morokuma, K., Eds.; American Chemical Society: Washington, D.C.; pp 473-488
  27. Scheuring, J., Berti, P. J. & Schramm, V. L. (1998) Biochemistry 37:2748-2758
    Pertussis Toxin: Transition State Structure for ADP-ribosylation of Recombinant Giα1 Subunits
  28. Berti, P. J., Blanke, S. R. & Schramm, V. L., (1997) J. Am. Chem. Soc. 119:12079-12088
    Transition State Structure for the Hydrolysis of NAD+ Catalyzed by Diphtheria Toxin
  29. Berti, P. J. & Schramm, V. L. (1997) J. Am. Chem. Soc. 119:12069-12078
    Transition State Structure of the Solvolytic Hydrolysis of NAD+